This is initially a 2-year fixed term role with the possibility of extension based on performance and budgetary considerations.
SCHOOL/UNIT DESCRIPTION:
Sarafan ChEM-H is an interdisciplinary institute focused on connecting Chemistry, Engineering, and Medicine for Human Health. The institute was founded as a joint venture of the Schools of Medicine, Engineering, and Humanities and Sciences. The proximity of world-class biologists, chemists, engineers, and clinicians at Stanford presents a unique opportunity to study human biology at a molecular level, to translate this knowledge into groundbreaking discoveries that advance our understanding of and ability to improve human health. Sarafan ChEM-H partnered with Stanford Medicine to launch a bold translational research initiative - Stanford's Innovative Medicines Accelerator (IMA). IMA aims to accelerate the translation of scientific discoveries at Stanford University into new therapeutics that impact human health while improving our understanding of human biology.
Our VPDoR Diversity Journey:
We create a hub of innovation through the power of diversity of disciplines and people.
We provide equitable access and opportunity to all members of the community in order to do their best work, regardless of race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
We listen to and value all colleagues who bring diverse perspectives to the advancement and development of a respectful community.
We promote a culture of belonging, equity, and safety.
We embed these values in excellence of education, research, and operation.
The Stanford IMA is seeking a motivated Molecular Pharmacologist to join our team to use their skills in exploring the activity of newly synthesized small molecules in your novel biochemical, cellular, or organoid-based assays. This is an full-time in-person position that requires strong interpersonal skills and in interactive and communicative style. You will use your expert knowledge of enzymology, biochemistry, and biophysical techniques to devise quantitative medium throughput assays to characterize the biochemical activities of novel small molecules. You may employ allied skills in cell and organoid assay development to complement these activities. You will be expected to be able to work independently in your area of expertise while interacting with other biologists, high-throughput screening experts, pharmacologists and medicinal chemists as part of several multidisciplinary teams. The Molecular Pharmacologist will also develop, optimize, validate, and perform enzymatic, biochemical, and biophysical assays for highly novel molecular targets as part of Stanford's Innovative Medicines Accelerator (IMA). They will work closely with our medicinal chemists to evaluate the activity of new small molecules in these assay systems with the goal of rapidly translating new biological discoveries into prototypical drug molecules.
We hope to find an individual who enjoys the opportunities for growth and development this position and being a member of the Stanford community provide. Come join this bold new initiative in an exciting intellectual environment!
CORE DUTIES:
Design research approaches for a major portion of research project(s), including background research, experimental design and execution, problem solving, and writing up for publication.
Develop new protocols; test and evaluate a variety of approaches.
Perform complex (lab and/or field) experiments and maintain detailed records of experiments and outcomes; analyze and interpret research data resulting from original procedures and methods.
Assist with new research proposals and applications for funding and grants.
Lead or participate in multidisciplinary teams across different faculties or schools.
Prepare periodic progress reports or written reports on all phases of the research project.
Contribute substantially to the preparation of papers for publication, especially in the results section. May be a co-author on publications. Present ongoing work and findings to colleagues at academic conferences.
Perform ongoing literature review to remain current with new procedures and related research; propose new research directions based on new advances discussed in literature.
Oversee supply and equipment budget under minimal supervision of principal investigator or business manager.
Formally supervise and train new staff or students as needed, including hiring, performance management, and related duties, in addition to instruction on techniques and consultation on project work.
MINIMUM REQUIREMENTS: Education & Experience: Bachelor's degree in related scientific field and four years of relevant work experience; or Master's degree in a related scientific field and two years relevant experience; or PhD in related science field.
Knowledge, Skills and Abilities:
Comprehensive understanding of scientific principles.
Expert level knowledge and skills in field of science related to research project. General computer skills, experience with databases and scientific applications, and ability to quickly learn and master computer programs.
Strong analytical skills and excellent judgment.
Ability to work under deadlines with general guidance is essential.
Excellent organizational skills and demonstrated ability to complete detailed work accurately.
Developing project management skills.
PREFERRED QUALIFICATIONS and EXPERIENCE:
PhD and post-doctoral experience in Biochemistry, Chemical biology, Molecular Pharmacology or related field.
Co-authorship or authorship on publications that demonstrate expertise in the field of biochemistry.
First-hand experience with mathematical analysis of enzyme kinetic and equilibrium binding measurements.
Industry experience in the evaluation of small molecule drug candidates.
Certifications and Licenses: None
PHYSICAL REQUIREMENTS*:
Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
Must have correctable vision to perform duties of the job.
Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
Ability to lift heavy objects weighing up to 50 pounds.
Ability to work in a dusty, dirty, and odorous environment.
Position may require repetitive motion.
* Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities. Applicants requiring a reasonable accommodation for any part of the application or hiring process should contact Stanford University Human Resources by submitting a contact form.
WORKING CONDITIONS:
May require working in close proximity to blood borne pathogens.
May require work in an environment where animals are used for teaching and research.
Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
May require extended or unusual work hours based on research requirements and business needs.
WORK STANDARDS:
Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors based on training and lessons learned.
Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu.
For On-site positions:
The expected pay range for this position is $93,062 to $111,670 per annum.
Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on a wide range of factors that are unique to each candidate including but not limited to geographic location, knowledge, skills and abilities, relevant education, depth and breadth of experience, performance; as well as other business and organization needs such as (but not limited to) the scope and responsibilities of the position, the minimum qualifications, departmental budget availability, and market and internal equity across the unit, department and reporting relationships.
At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford's extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process.
Why Stanford is for You
Imagine a world without search engines or social platforms. Consider lives saved through first-ever organ transplants and research to cure illnesses. Stanford University has revolutionized the way we live and enrich the world. Supporting this mission is our diverse and dedicated 17,000 staff. We seek talent driven to impact the future of our legacy. Our culture and unique perks empower you with:
Freedom to grow. We offer career development programs, tuition reimbursement, or audit a course. Join a TedTalk, film screening, or listen to a renowned author or global leader speak.
A caring culture. We provide superb retirement plans, generous time-off, and family care resources.
A healthier you. Climb our rock wall, or choose from hundreds of health or fitness classes at our world-class exercise facilities. We also provide excellent health care benefits.
Discovery and fun. Stroll through historic sculptures, trails, and museums.
The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.
Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
Why work at Stanford?Stanford University has changed the world, over and over again.We are one of Silicon Valley's largest employers - and also one of the most unique. Our mission is to educate future leaders and promote interdisciplinary, world-class research and teaching. This passion makes Stanford an intensely creative, rewarding, and challenging place to work. At the same time, our traditions of respect and collaboration sustain a humane, supportive environment in which to pursue your life and your career.At Stanford you'll work with bright, diverse, dedicated people. You'll find encouragement to learn and grow. You'll enjoy excellent benefits and an outstanding environment. How will it change you?
