We seek a highly motivated and enthusiastic research technologist who will thrive in a fast-paced basic and translational mucosal immunology lab within the Mucosal Immunology and Biology Research Center of the Department of Pediatrics at Mass General Hospital. As a lab member, the technologist will interact with a multidisciplinary group of faculty, postdocs, graduate students, and research assistants from different backgrounds, including mucosal immunology, microbiology, gnotobiology, and metabolism. The technologist will have the opportunity to learn unique methods while working on our projects on how early-life host-microbial interactions in the intestine modulate the risk of developing disease in the neonatal period and beyond, particularly obesity. The technologist will work closely with the principal investigator, a neonatologist and mucosal immunologist, in performing in-vivo and in-vitro experiments at the interface of mucosal immunology, microbiology, and metabolism using transgenic mice and human samples. Duties require a person with experience in wet lab research and experience or training upon the hiring of the use of experimental mice.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
Assist the PI(s) with determining the most suitable methodology to address research questions cost-effectively.
Plan experiments closely with the PI with gradual independence according to experience.
Execute experimental protocols and help develop new protocols to address the research questions.
Organize and summarize acquired data using scientific and statistical techniques, maintaining an electronic lab notebook.
Analyze results and may begin interpretation of results.
Manage and track research project progress through regular communication with PI.
Maintains and orders supplies.
Prepares lab chemicals and maintains instruments and equipment.
Maintains tissue culture.
Responsible for IACUC and IRB submissions, including preparation and submission of new protocol applications, annual review forms, adverse event reporting, and drafting amendments in keeping with protocol and/or staff changes.
May perform independent literature searches.
Assists with organizing materials and documents for grants, publications or presentations.
Attend and/or present at internal meetings/seminars.
If appropriate to level of experience, review work of trainees, assist with training, and assume a leadership role in planning lab activities.
Incumbent must be able to learn many complicated, technical details over a short period and carry out procedures meticulously, taking action to prevent mistakes.
Incumbent should be prepared to occasionally work evenings and on weekends to perform some experiments, including being on call during weekends to respond to technical problems in the lab.
Incumbent should be able to show initiative & confidence in making decisions.
Incumbent should not easily be discouraged by failed experiments but enjoy the challenge.
Elements of project management will be required to stay on top of the multiple projects the lab has running in parallel.
Ability to work independently and improve the quality and efficiency of one's work.
Good interpersonal and communication skills.
A sound degree of computer literacy & willingness to advance computational skills independently.
Ability to perform multiple tasks independently, manage their time well and adapt to changing priorities.
Ability to work well on a team and enlist others' support in achieving objectives.
Incumbent must be comfortable with mouse work or willing to learn upon joining the lab.
Analytical skills and the ability to resolve technical problems.
Ability to interpret acceptability of data results.
Demonstrated competence in research techniques and methodologies.
Bachelor's degree in biological or physical sciences. MA/MS/MPH preferred.
3+ years of directly related laboratory experience preferred.
EEO Statement Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.Partner's Healthcare is acting as an Employment Agency in relation to this vacancy.
MGH Institute of Health Professions, founded by Massachusetts General Hospital in 1977, is an innovative and independent graduate school in Boston that is a member of Partners HealthCare. A progressive leader in developing comprehensive models of health care education, the MGH Institute prepares advanced practice professionals in the fields of nursing, physical therapy, occupational therapy and communication sciences and disorders through a distinctive combination of academic study, clinical practice, and research. More than 1,200 students are enrolled in graduate level and certificate programs, with an increasing number of courses available online. The Institute is accredited by the New England Association of Schools and Colleges (NEASC).