Details
Posted: 18-Jun-22
Location: Beaverton, Oregon
Type: Full-time
Salary: Open
Categories:
Research
Department Overview
The Vaccine and Gene Therapy Institute (VGTI) at Oregon Health & Science University (OHSU) has assembled a multidisciplinary team of scientists to respond to serious viral disease threats, including AIDS, chronic viral infection-associated diseases, newly emerging viral diseases and infectious diseases of the elderly. Our programs are intended to span the continuum between basic and clinical science, in which discoveries are rapidly advanced from the level of molecular and cellular biology through animal models and ultimately into clinical testing. The development of this unique program in immunology and virology provides an important training opportunity for graduate students and postdoctoral fellows at OHSU. This is why an important part of our mission is the training of young scientists in newer academic disciplines emerging at the Vaccine and Gene Therapy Institute.
Function/Duties of Position
Uncontrolled inflammation generates significant morbidity and mortality in many infectious (e.g. HIV) and non-infectious (e.g. inflammatory bowel disease) diseases. By utilizing non-human primate models of human disease (both viral and non-viral etiology), the Estes Laboratory works to elucidate determinants of local and systemic inflammation leading to tissue pathology, disease progression, and viral reservoir persistence, as well as tests therapeutics to modulate the immune landscape, restore immune homeostasis, and reduce viral reservoirs.
This position will be a part of the operations team in the Estes Laboratory. The primary purpose of this position will be to organize samples for active studies in addition to database maintenance of historic samples and reagents. This position will also be involved with maintaining laboratory supplies and equipment. This position receives general supervision.
- Experience with database organization is highly desired.
- Knowledge of aspects of standard pathology techniques (e.g. microtomy and staining) is preferred.
- Additionally, this individual will work in collaboration with other members of the laboratory to support experiments for a variety of projects, which may involve handling and processing of non-human primate samples and human clinical trial samples.
- General laboratory methods expected of this position include cell isolation, microtomy, directed immunohistochemistry, reagent testing, use of manual and automated staining platforms (i.e. intelliPATH and Bond RX), multiplexed in situ hybridization and protein immunofluorescence, and multispectral imaging.
- Background in a relevant immunology, ideally in HIV/SIV, is desirable.
Required Qualifications
Education: Bachelors in relevant field OR Associates AND 3 years of relevant experience OR 4 years of relevant experience
Experience:
- Must have basic laboratory skills- pipetting, ability to make calculations.
- Must have excellent communication, analytical and organizational skills: both written and verbal.
- Comfortable with tissue processing and handling.
- Ability to prioritize and execute multiple tasks in a work day.
- Ability to work independently and as part of a team.
- Ability to work on a computer for 5 continuous hours a day.
- Problem solving skills with the ability to listen, understand, and solve issues.
- Ability to always demonstrate the highest level of performance and behavior standards.
- Ability to be honest and straightforward, dealing with issues fairly and consistently.
- Ability to be a team player. Support and assist team members. Be available to help, and learn from the team. Keep an open mind to feedback, and earn trust of staff and providers.
- Ability to use tact and diplomacy to maintain effective working relationships.
Job related knowledge, skills, and abilities:
- Must be proficient with computers running Apple and Windows/PC applications (e.g. MS Word, Excel, Access, and PowerPoint).
- Willingness to work with pathogens potentially dangerous to humans
- Willingness to work in Biosafety Level 2 and 3 facilities
- Willingness and ability to work flexible hours
- Ability and willingness to work independently
- Ability to carry and lift 35 lbs.
- Ability to stand for three continuous hours a day
- Ability to work on computer for five continuous hours a day
- Able to perform the essential functions of the position with or without accommodation
Preferred Qualifications
Experience: Experience/Knowledge of preparing cryostat sections, immunohistochemistry, imaging using an array of platforms; serum, plasma, and mononuclear cell isolation
Job related knowledge, skills, and abilities:
- Database entry and organization.
- Experience conducting laboratory research in an academic setting.
- Familiar with whole slide digital imaging.
- Experience in Microtomy.
- Knowledge of multiplexed immunofluorescence and in situ hybridization based methods.
- Previous experience or education in HIV/SIV disease and research.
- Prior experience working with non-human primates and/or non-human primate derived specimens.
Registrations, Certifications and/or Licenses: Histotechnician, HT (ASCP), Histotechnologist, HTL (ASCP) certified and/or Medical Technologist, MT (ASCP)
All are welcome
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or
[email protected] As an organization devoted to the health and well-being of people in Oregon and beyond, OHSU requires its employees to be fully vaccinated against COVID-19.
