The Technician B will perform research requiring excellent application of professional judgment, interpretation of experimental results and collaboration with other lab members. Qualified candidates will have a strong background in molecular/cellular biology and experience with in vivo animal studies and handling of animals. In addition, competitive candidates will be proficient with molecular cloning, CRISPR/Cas9 gene editing, metabolomics, and a wide spectrum of molecular, biochemical, and cellular assays. Excellent written and communication skills, ability to effectively collaborate with fellow scientists, and execute tasks in a timely manner are highly desired. This position offers the motivated technician an opportunity to participate in project-based research, as well as authorship on a manuscript.
The incumbent will perform molecular, cell biology and genetic studies in both in vitro and in vivo cancer models. DNA and RNA preparation, PCR, recombinant DNA cloning, gel electrophoresis, Western blots and tissue culture; · Oversight and maintenance of mouse colony. Work with and handling research animals. · Assist lab staff with animal surgeries, dissections, tissues sectioning, immunohistochemistry, and related work. · Data analysis, identification of methodological problems in research protocols. · Operate and help maintain common lab equipment. · Assist in general lab organization and inventories maintenance. · Generate and present written or oral progress reports, including assembly, organization, and interpretation of data. Additional responsibilities pertain to laboratory safety, organizing supplies, research reagents, equipment maintenance, monitoring and ordering lab supplies and other related duties as required.
Requires a Bachelor's degree in Biology, Molecular Biology, Biochemistry, Chemistry or related field or equivalent combination of education, training and experience.
Computer skills a must (word/excel).
Good interpersonal communications skills are required.
It may be necessary to work late on occasion to complete experiments.
Excellent organizational skills and communication skills (written and oral)
Experience with mouse models, in vivo drug administration, cell biology assays e.g. flow cytometry, and/or molecular biology techniques is desired.
0-6 months laboratory experience.
Previous experience in 3D cell culture, and/or project management is desired, but not required.
Ability to work well in a multidisciplinary team environment
· Make sound decisions based on knowledge and experience.
· Prior experience working with mice in a research setting · Able to learn complex tasks with general instruction, and to use experience to perform a variety of new techniques · Generate presentations. · Ability to review data and information critically.
· Conduct literature reviews to determine suitable research methods. · Assist the PI with writing of protocols.
No special indicators.
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 513550
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