The Wyss Institute for Biologically Inspired Engineering at Harvard University seeks a Research Assistant to assist our Bioinformatics team to build our internal and external apps/tools that help scientists organize, analyze, and visualize their biological results.
This role involves working closely with our researchers, including faculty, staff scientists, engineers, and post-docs to gather requirements for bioinformatics analysis supporting patent development, grant applications, progress reports and academic publications.
This candidate must have a demonstrated proficiency in the analysis of ssRNA-seq, RNA-seq and microarray transcriptomics data. Specifically, this includes file processing, quality control checking, data normalization, differential expression analysis, data visualization, and generating high-quality plots for publication. Background in pharmacology, cancer biology, or immunology is preferred. Experience analyzing additional -omics types (e.g. metabolomics, proteomics) is a plus.
The candidate must be proficient in git. In this role, you will be responsible for managing biological data storage as well the integration of APIs (e.g. DrugBank) into new and existing pipelines and applications. You will also be expected to write and adapt in-house Shiny apps in order to modularize analysis scripts and make them easy for all researchers to apply.
Overall, in this role, you will contribute to the Wyss Institute culture of innovation and collaboration by developing tools that augment cutting-edge research across multiple areas of the Institute.
Specific areas of responsibility include:
In collaboration with bioinformatics team, advise and consult with wet lab scientists across multiple labs on experimental design, analysis, and visualization strategies for a diverse set of scientific research programs (SARS-CoV-2, influenza, microbiome, and more)
With minimal supervision, analyze ssRNA-seq, RNA-seq, and microarray transcriptomics data according to best practices, evaluating data quality and providing thorough biological interpretation of results
Support the design of novel algorithms to test scientific hypotheses using transcriptomics and other - omics experiments
Contribute to the authoring, designing, and optimizing of new and existing Shiny applications Managing software licenses, user permissions, and biological database storage and management
This is a one year term position with the possibility of renewal.
The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances and launching startup companies. For more information, visit: http://wyss.harvard.edu/.
Harvard offers an outstanding benefits package including:
Time Off: 3 - 4 weeks paid vacation, paid holiday break, 12 paid sick days, 11.5 paid holidays, and 3 paid personal days per year.
Medical/Dental/Vision: We offer a variety of excellent medical plans, dental & vision plans, all coverage begins as of your start date.
Retirement: University-funded retirement plan contributions from 5% to 15% of eligible compensation, based on age and earnings with full vesting after 3 years of service.
Tuition Assistance Program: Competitive tuition assistance program, $40 per class at the Harvard Extension School and discounted options through participating Harvard grad schools.
Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
Wellness options: Harvard offers programs and classes at little or no cost, including stress management, massages, nutrition, meditation and complimentary health services.
Harvard access to athletic facilities, libraries, campus events and many discounts throughout metro Boston.
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Salary Grade: 054
Union: 55 - Hvd Union Cler & Tech Workers
Bachelor's degree in science, engineering or related field required.
A minimum of two years experience working with Bioinformatics required. Advanced education may count towards years of experience.
Proficiency in the R programming language required. Experience with R Shiny is highly preferred.
Advanced degree in biological science (especially pharmacology, cancer biology, or immunology) or bioengineering is strongly preferred.
Clear technical written and oral communication skills are essential, and the candidate should be highly independent, detail-oriented, organized, and motivated to take initiative. Experience with Python and Agile development and project management tools (e.g. Jira, Zenhub, Clubhouse, Trello) is a plus.
EQUAL OPPORTUNITY EMPLOYER: We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.
Internal Number: 52604BR
About Harvard University Medical School
Harvard University is devoted to excellence in teaching, learning, and research, and to developing leaders in many disciplines who make a difference globally. The University, which is based in Cambridge and Boston, Massachusetts, has an enrollment of over 20,000 degree candidates, including undergraduate, graduate, and professional students. Harvard has more than 360,000 alumni around the world. The University has twelve degree-granting Schools in addition to the Radcliffe Institute for Advanced Study, offering a truly global education. Established in 1636, Harvard is the oldest institution of higher education in the United States.