Med-Anesthesiology and Perioperative Medicine - Pennsylvania-Pittsburgh - (20002834)
The Department of Anesthesiology and Perioperative Medicine within the School of Medicine is seeking a Laboratory Supervisor of Amygdala Research, Mouse Transgenics Core Director, and Microscopy Core Director who will coordinate studies of neural circuitry and gene expression in transgenic mouse lines. We discovered a new lipid receptor mechanism in the amygdala by which the body naturally puts on the brakes to prevent the transition from acute injury to chronic pain. The incumbent will collaborate within a large basic science team to co-manage a program of research to continue these studies and to ultimately generate new non-opioid pharmacotherapies and analgesic drugs for neurotrauma, arthritis, diabetes, and multiple sclerosis.
This position: - As Laboratory Supervisor of Brain Research, oversees data entry and analysis. Trains staff in Microsoft Excel, Word, and Powerpoint, and statistical analysis software including Graphpad Prism, Minitab, SAS, and R. Assists the PI with technical writing and editing of Methods and Results, research consolidation and critical analysis, and educational and training material development to generate Standard Operating Procedures. Manages and makes high level decisions on the ordering (using Quartzy) and procurement of all laboratory equipment and supplies, and maintains all necessary records and documentation.
- As Mouse Transgenics Core Director, supervises part-time employees and Research I-III staff in the management of a transgenic mouse colony including handling, husbandry, genotyping using chemical and DNA extraction and PCR protocol development and primer design,. Coordinates studies involving affective and pain-like behavioral assays in mice. Develops and maintains high fidelity system to maintain records and track mouse breeding and inventory.
- As Microscopy Core Director, coordinates tissue collection and processing of mouse tissues for fluorescent immunohistochemistry and RNAscope in situ hybridization, and trains and coordinates use of high power fluorescent microscopes.
A total of at least seven years cumulative experience and that spans all of the following can be substituted for advanced degree requirements: research methods and talents: observation and behavioral monitoring in vertebrates; genetics; veterinary care and examination; development or ordering and inventory systems; expertise with Quartzy; investigation of funding opportunities; supervisory experience including digitized supply management systems; onboarding trainer and supervisor and scheduler of new team members, general biological research including identification and inventory of biological specimens; neuroscience laboratory research; immunohistochemistry of brain tissue slices; in situ hybridization RNA scope in the mouse brain; technical writing and editing publication skills, using Microsoft Excel, Word, and Powerpoint and statistical analysis software including Graphpad Prism/Minitab/SAS/R; rodent handling and behavioral analysis including pain behavior; maintenance of transgenic mouse colonies including breeding, genotyping, inventory.
The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity and diversity. EOE, including disability/vets
Assignment Category: Fulltime-Regular
Job Classification: Staff.Research.IV
Minimum Education Level Required: Master's
Minimum Experience Level Required: 3-5 years experience
Work Schedule: Monday-Friday, 8:15 am - 4:45 pm
Hiring Range: $30,732.00 - $49,296.00
Relocation Offered: No
Visa Sponsorship Provided: No
Background Check: For position finalists, employment with the University will require successful completion of a background check
Child Protection Clearances: Not Applicable
Required Documents: Resume, Cover Letter
Internal Number: 20002834
About University of Pittsburgh
Founded in 1787, the same year the U.S. Constitution was signed, the University of Pittsburgh is one of the oldest institutions of higher education in the United States. One of three state-related research universities in Pennsylvania, Pitt is a member of the Association of American Universities (AAU), which comprises 62 preeminent doctorate-granting research institutions in North America.Pitt faculty members have expanded knowledge in the humanities and sciences, earning such prestigious honors as the National Medal of Science, the MacArthur Foundation’s “genius” grant, the Lasker-DeBakey Clinical Medical Research Award, and election to the National Academy of Sciences and the Institute of Medicine. Pitt scientists have defeated polio, unlocked the secrets of DNA, lead the world in organ transplantation, and pioneered TV and heavier-than-air flight, among numerous other accomplishments.Pitt students have earned Rhodes, Goldwater, Marshall, and Truman Scholarships, among other highly competitive national and international scholarships.Alumni have pioneered MRI and TV, won Nobel and Pulitzer Prizes, led corporations and universities, served in government and the military, conquered Hollywood and The New York Times bestsellers list, and won Super Bowls and NBA championships.