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The new Brotman Baty Institute for Precision Medicine is looking for a candidate to fill a Research Scientist I, Saturation Genome Editing position, a unique scientist position at the intersection of cutting edge technology development and medicine. The institute bridges the University of Washington, the Fred Hutchinson Cancer Research Center and Seattle Children’s Hospital. The Advanced Technology Lab (BAT-lab) is a new entity within this institute, and will be administratively located within the Department of Genome Sciences at the University of Washington. The mission of the Advanced Technology Lab will be to make cutting-edge ‘-omics’ technologies, including many developed by labs at the member institutions, broadly available to the Institute’s research community.
We seek an individual with strong molecular biology skills for the Advanced Technology Lab at the Brotman Baty Institute. The scientist will be responsible for:
1) performing saturation genome editing •Prepping RNA and DNA from edited cells •PCR amplification of edited regions from genomic DNA and RNA •Maintaining tissue culture cells •Molecular cloning of libraries and guides.
Background on the University of Washington and Genome Sciences:
The Department of Genome Sciences (GS) is part of the University of Washington School of Medicine and is comprised of 30 labs addressing leading edge questions in biology and medicine by developing and applying genetic, genomic and computational approaches taking advantage of genomic information now available for a host of species. GS is making major contributions in the application of genome science to understand the fundamentals of biology and to improve human health and wellbeing. Genome Sciences is a collaborative department supported by very different academic disciplines. We work with a multitude of Program Investigators (PIs) in departments both on the UW campus as well as worldwide. The department has gone through significant expansion since its beginning in 2001 with annual grant awards of $57M in FY20. The department has 62 training, teaching, and research faculty.
Scientific Operations (70%):
· Prep RNA and DNA from cells · Tissue culture · PCR amplification of editing regions · cloning and plasmid prep
Project Management (20%)
· Keep BATlab project management tools up to date to integrate with production schedule · Plasmid and nucleic acids prep organization and management
· Meet with collaborators to learn and incorporate best practices for genome editing · Attend Shendure lab meetings and meetings for the Center for Multiplexed Assessment of Phenotype
· Bachelor’s degree in molecular biology, cellular biology, genetics or related discipline, or equivalent experience. · 1 year of lab experience in cell or molecular biology. This can be at the undergraduate level. We are seeking candidates that are eager to learn new skills as part of the single cell team. · Candidate should have an outstanding academic and professional track record. · Candidate should be an innovative and analytical thinker with outstanding interpersonal and communication skills. Must be highly disciplined and organized. · Successful candidate will be highly self-motivated and enthusiastic about taking a hands-on approach to collaborative scientific discovery efforts.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
· Experience in cell or molecular biology, specifically Illumina sequencing, PCR or tissue culture.
As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here.
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