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RESEARCH SCIENTIST I, Saturation Genome Editing
University of Washington
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RESEARCH SCIENTIST I, Saturation Genome Editing

University of Washington

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Details
Posted:
August 21, 2020
Location:
Seattle, Washington
Salary:
Open
Type:
Full Time

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. All of which has allowed the UW to be nationally recognized as a “Great College to Work For” for six consecutive years. 

The new Brotman Baty Institute for Precision Medicine is looking for a candidate to fill a Research Scientist I, Saturation Genome Editing position, a unique scientist position at the intersection of cutting edge technology development and medicine. The institute bridges the University of Washington, the Fred Hutchinson Cancer Research Center and Seattle Children’s Hospital. The Advanced Technology Lab (BAT-lab) is a new entity within this institute, and will be administratively located within the Department of Genome Sciences at the University of Washington. The mission of the Advanced Technology Lab will be to make cutting-edge ‘-omics’ technologies, including many developed by labs at the member institutions, broadly available to the Institute’s research community.

We seek an individual with strong molecular biology skills for the Advanced Technology Lab at the Brotman Baty Institute. The scientist will be responsible for:

1) performing saturation genome editing 
•Prepping RNA and DNA from edited cells
•PCR amplification of edited regions from genomic DNA and RNA
•Maintaining tissue culture cells
•Molecular cloning of libraries and guides.

Background on the University of Washington and Genome Sciences:

The Department of Genome Sciences (GS) is part of the University of Washington School of Medicine and is comprised of 30 labs addressing leading edge questions in biology and medicine by developing and applying genetic, genomic and computational approaches taking advantage of genomic information now available for a host of species. GS is making major contributions in the application of genome science to understand the fundamentals of biology and to improve human health and wellbeing. Genome Sciences is a collaborative department supported by very different academic disciplines. We work with a multitude of Program Investigators (PIs) in departments both on the UW campus as well as worldwide. The department has gone through significant expansion since its beginning in 2001 with annual grant awards of $57M in FY20. The department has 62 training, teaching, and research faculty.

Responsibilities

Scientific Operations (70%):

·    Prep RNA and DNA from cells
·    Tissue culture
·    PCR amplification of editing regions
·    cloning and plasmid prep

Project Management (20%)

·       Keep BATlab project management tools up to date to integrate with production schedule
·       Plasmid and nucleic acids prep organization and management

Collaboration (10%):

·       Meet with collaborators to learn and incorporate best practices for genome editing
·       Attend Shendure lab meetings and meetings for the Center for Multiplexed Assessment of Phenotype

Requirements include:

·       Bachelor’s degree in molecular biology, cellular biology, genetics or related discipline, or equivalent experience.
·       1 year of lab experience in cell or molecular biology. This can be at the undergraduate level. We are seeking candidates that are eager to learn new skills as part of the single cell team.
·       Candidate should have an outstanding academic and professional track record.
·       Candidate should be an innovative and analytical thinker with outstanding interpersonal and communication skills. Must be highly disciplined and organized.
·       Successful candidate will be highly self-motivated and enthusiastic about taking a hands-on approach to collaborative scientific discovery efforts.

Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.

Desired:

·        Experience in cell or molecular biology, specifically Illumina sequencing, PCR or tissue culture.

As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here.

Application Process:

The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process.  These may include Work Authorization, Cover Letter and/or others.  Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.

Internal Number: 181811
About University of Washington
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.
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