UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. All of which has allowed the UW to be nationally recognized as a “Great College to Work For” for six consecutive years.
UW Medicine LMP brings together state-of-the-art technology and highly trained, world renowned personnel to provide comprehensive diagnostic and personalized service to physicians, community hospitals, independent laboratories, and other health care organizations. Our operations are based at the University of Washington Medical Center, Harborview Medical Center, South Lake Union, Northwest Hospital and the Seattle Cancer Care Alliance. Pathology faculty members also serve at Seattle Children's Hospital, the Veteran’s Administration Puget Sound Healthcare System, and the Fred Hutchinson Cancer Research Center. These collaborative efforts have generated innovative, translational studies in the basic mechanisms of disease as they apply to diagnostic pathology.
The Department of Laboratory Medicine and Pathology has an outstanding opportunity for a full-time Senior Research Scientist.
The UW BioRepository and Integrated Neuropathology (BRaIN) Research Laboratory’s mission is to advance human brain science, with emphasis on brain aging and neurodegeneration, neurotrauma, and neurooncology, through human brain donation and analysis using, and developing, the latest quantitative methods. The BRaIN lab has an outstanding opportunity for a highly specialized Senior Research Scientist to perform neuropathological examinations of human brain tissue, collect data and update the neuropathology research database, and perform data analyses on the data collected as part of multiple ongoing research projects in the laboratory. The position is focused on recognition of common and novel structural changes associated with neurodegenerative disease, acute and late effects of neurotrauma, and brain aging, recording findings in database format and updating database with new findings, and analyzing these findings, interpreting these findings across regions, individuals, and cohorts, and interfacing with principle investigators to disseminate findings.
Under the general supervision of the Principle Investigator, the senior research scientist will be responsible for/participate in all aspects of neuropathological analysis of human brain specimens. The typical job duties for this position include:
•The preparation, examination, and documentation of neuropathologic examination of human brain specimens for research including:
oIndependent gross examination; oDissections (fresh, frozen, and fixed); oTissue processing; oHistologic preparation and staining oAnalysis of histopathologic findings oDevelopment of histochemical, immunohistochemical, and non-traditional tissue analytical techniques oReporting gross and neuropathologic findings oIntegration and interpretation of findings in a comprehensive report
•Control and administration of new and archived research autopsy materials including:
oFrozen tissue; oFixed paraffin-embedded tissue blocks; and oFixed “wet” tissue;
•Participation in quantitative analytical approaches, particularly including digital image analysis, unbiased stereology, and other protein and nucleic acid-based approaches
•Neuropathological data analysis and interpretation and communication with principle investigators and through seminars and clinicopathologic conferences
•Supervision and training of lab personnel (junior research scientists, students, etc.)
•Significantly contribute and/or co-author manuscripts and present research results
•Plan and conduct research work requiring independent judgment in the evaluation, selection, and substantial adaptation/modification of standard neuropathological techniques, procedures and criteria
The successful applicant will also be expected to participate in lab and other meetings, provide regular progress updates, review work lists and prioritize work in conjunction with the PI and interact with the research team and collaborators. The successful applicant will contribute to maintaining updated records and protocols in the lab and will work collaboratively with lab personnel to assess and enhance the project plan and implement new approaches to project tasks. Finally, the senior research scientist will be expected to assist with a variety of special projects, and research related duties as assigned in a dynamic and fast-changing research environment where innovation and novel analytic applications form the foundation of an integrated model of precision neuropathology.
This position has operational access to patient health information and clinical materials including pathology specimens and archival blocks and slides, and for these activities must adhere to the covered entity HIPPA Privacy and CLIA rules and has 'dotted line' reporting to the CLIA certificate holders and applicable clinical laboratory management staff.
Advanced Degree (MD, PhD, or equivalent with coursework in physiology, pathology, biology and other biological sciences.
Minimum of 3 years’ experience in a related area or equivalent combination of education and experience, including significant exposure to microscopic analysis; some or all may be in relevant educational programs.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
Diagnostic neuropathology experience, particularly in autopsy neuropathology
Experience in a neurodegenerative brain biorepository/neuropathology core
Conditions of Employment:
UW Research Scientists are essential to BRaIN research laboratory activities; this position requires work after-hours, weekends and or outside normal business hours.
As a UW employee, you will enjoy generous benefits and work/life programs. For a complete description of our benefits for this position, please visit our website, click here.
The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.