Department: MED-Center for Genetic Med Salary/Grade: NEX/14
Northwestern University Genomics Facility NUSeq is looking to hire a Clinical Genomics Specialist to kickstart the Facility’s newly launched initiative on clinical sequencing and genomics services. The position will be leading the Facility’s efforts to establish and maintain CLIA lab accreditation, establish new clinical sequencing/genomics services, and collaborate with the Facility’s bioinformatics team on downstream data processing and reporting. The NUSeq’s Clinical Genomics Services to be launched will encompass next-gen sequencing (NGS) services including whole genome sequencing, whole exome sequencing, targeted gene panel sequencing, and services based on other genomics technologies such as microarray, as well as nucleic acid extraction from patient samples. The position will have ample support from and interactions with bioinformaticians and pathologists.
The NUSeq Facility of Northwestern University provides state-of-the-art genomics instrumentation, informatics, and technical know-how to support clinical practice, translational, and basic research at Northwestern University and Northwestern Medicine. Located at Northwestern’s Feinberg Medical School on the Chicago Campus, NUSeq currently provides over 60 genomics services to scientists at Northwestern on both Evanston and Chicago campuses. These services cover a broad range of technologies, from NGS, microarray, Sanger sequencing, automated DNA extraction, DNA/RNA sample QC, cell line authentication, real-time quantitative PCR, to droplet digital PCR.
NUSeq’s new Clinical Genomics Initiative is built upon the Facility’s rapid growth since establishment in 2015, with operation budget now over $2.5M annually. With this position, the Facility looks to hire a new colleague with clinical NGS experience in a CLIA environment. NUSeq invites you to join a highly collegial and productive team to lead the new initiative on Clinical Genomics, which is launched to support Northwestern Medicine’s push on the new front of personalized medicine. Northwestern Memorial Hospital is ranked No. 1 in the Chicago Metro area and Illinois, and a top 10 hospital in the nation based on U.S. News & World Report for 2019-20.
**May work off normal hours due to delivery of critical clinical samples.
Ensures client billing information is complete and accurate.
Compiles billing information for documenting usage and billing information into the Core's automated service tracking/billing system.
Develops cost analyses on services rendered by the Core.
Assists in preparing cost quotes on experimental design requested by investigators.
Ensures that all work is accurately and completing documented.
Interacts with both Core Staff and clients in the planning and execution of experiments/ core services.
Advises PIs as appropriate.
Responsible for the Core's compliance with safety protocols, relative to the use of combustibles, radioactivity, toxic material, and/or carcinogenics.
Ensures sterile conditions as required.
Plans, conducts and evaluates experiments and assays of varying complexity.
Understands, follows, and troubleshoots protocols.
Records, compiles, and reports data
Provides analysis and insightful interpretations of results.
Participates in beta-testing of new protocols and services.
Develops new methods or customizes protocols for users.
Ensures lab is prepared for service delivery (experimentation)
Ensures established inventory levels, and notes usage trends so that inventory levels meet client demand.
Ensures the recommended maintenance on instrumentation and equipment is performed according to manufacturer and University guideline.
Troubleshoots equipment problems, and mitigates the issues with training and/or repair protocols.
Recommends equipment improvements and/or new equipment.
Assists in the development of usage protocols for new equipment.
Ensures compliance with all University, sponsor and federal rules and regulations.
Using an advanced level of skill, completes the following activities:
DNA, RNA, isolation, purification and expression
Sequencing of DNA
pH meter, plate reader
Trains or assists in training of technicians and trainees including students.
Provides training to researchers in instrument and equipment operation.
Performs other duties as assigned
Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree;
4 years of technical or other relevant experience.
Minimum Competencies: (Skills, knowledge, and abilities.)
Adequate molecular biology lab skills, and good understanding of biochemical properties of nucleic acids and enzymes.
Preferred Qualifications: (Education and experience)
M.S. or doctoral degree in a life science discipline.
Preferred Competencies: (Skills, knowledge, and abilities)
Familiarity with the CAP/CLIA accreditation process.
Skilled in next-gen sequencing technologies, including preparation of libraries, sequencer operation, and run monitoring/troubleshooting.
Experienced in whole genome, exome, and gene panel sequencing of clinical samples.
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.
Internal Number: 38476
About Northwestern University
Northwestern University is a major private research university with 12 academic divisions located on three campuses in Evanston, Chicago, and Education City in Doha, Qatar. We have approximately 2,500 full-time faculty members, 17,000 graduate and undergraduate students, and over 5,700 full and part-time staff. Northwestern University combines innovative teaching and pioneering research in a highly collaborative environment. It provides students and faculty exceptional opportunities for intellectual, personal and professional growth.