The West Virginia University Department of Biochemistry is seeking applications for Postdoctoral Researcher. The candidate will be responsible for the carrying out research (80% effort) within currently funded NIH project as well as within other collaborative projects, managing effort (10%) and additional support and development effort (10%) as detailed below:
Serves as investigator in charge of the effort to advance Overhauser-enhanced magnetic resonance imaging (OMRI) and electron paramagnetic resonance (EPR) spectroscopy and imaging approaches for application for functional mapping of tumor microenvironment, including in vivo experiments in animal models of cancer developed and studied at the Health Science Center, Department of Biochemistry, West Virginia University. Duties will include testing and application of new paramagnetic probes in combination with EPR and OMRI modalities to visualize specific parameters of chemical tumor microenvironment such as oxygen, redox status, glutathione and interstitial inorganic phosphate. Duties will include obtaining preliminary data and contributing in the writing of manuscripts, articles, abstracts and research reports for publication in peer-reviewed journals, and training students.
RESEARCH - 80% To test and calibrate newly developed probes and develop acquisition and imaging reconstruction protocols for mapping functional parameters of local chemical microenvironment. To develop Overhauser-enhanced MRI methodology for functional tissue mapping, in vivo. To apply newly developed probes and imaging protocols in a mouse model of breast cancer using L-band EPR spectroscopy and OMRI. Use the knowledge accumulated to extend functional imaging of tumor microenvironment. Set up collaborations with known scientists in the field of functional biomedical imaging. To train and direct students towards executing methodologies.
MANAGEMENT - 10% Develops, summarizing research results for the new grant proposals, as well as in support of the research being undertaken. Collects, analyzes, interprets and evaluates data. Contributes in planning and writing manuscripts, articles, abstracts and research reports for publication in peer-reviewed journals. Attends and presents research findings at national and international scientific conferences, seminars, and workshops.
ADDITIONAL SUPPORT AND DEVELOPMENT - 10% Performs daily activities of lab, including if necessary maintenance of equipment, ordering of reagents, radiation supervision, and design of protocols. Investigates and evaluates current literature to set goals for current and new research projects and grants. Directs and instructs research assistants, and undergraduate and graduate students in techniques and other lab activities, and data analysis.
West Virginia University, founded in 1867, has a long and rich history as a public, land grant institution. WVU encourages scholarship, offers high quality academic programs while serving the state of West Virginia and the nation. WVU is located in Morgantown, West Virginia, has been ranked as a #1 Small City in America, with divisional campuses in Charleston, Keyser, Martinsburg, and Montgomery. WVU is a Research University (Highest Research Activity) and ranks among the top 100 public universities in the nation, including a top 15 ranking in most affordable tuition for out-of-state students. WVU offers 184 degrees throughout the 15 colleges and schools within the university. Areas of specialty include STEM education, healthcare in Appalachia, shale gas utilization, radio astronomy, and forensics. There are more than 32,000 graduate and undergraduate students along with 190,000 alumni worldwide who are pioneering, passionate, innovative, tireless and caring.