The Department of Radiology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for an Assistant Professor position in the non-tenure research track. Expertise is required in the specific area of the development of patient derived models of hepatocellular carcinoma as well as in studying the metabolic effects of the tumor micro-environment on cancer cells and/or using pooled screening approaches (such as pooled Crispr or shRNA screening). Formal training in managerial and supervisory skills as well as project management is required. A proven ability to analyze large biological datasets using R, matlab, etc. is a plus. Applicants must have a Ph.D. or equivalent degree. A Ph.D. in biological sciences or biophysics such as cancer biology, genetics, biochemistry, cell biology or molecular imaging is required. in addition, the applicant must have completed post-doctoral training of at least 5 years duration with experience applying molecular biology techniques to a cancer biology setting.
Research or scholarship responsibilities may include the study of image-guided interventions, cancer biology and molecular imaging. Qualified individuals will be expected to oversee general lab operations, supervise and mentor trainees, and assist other lab personnel with experimental procedures and analysis as well as to develop new projects and assist in grant writing. The successful applicant will be able to apply high throughput screening techniques including Crispr/Cas9 genome engineering in primary cells as well as utilize CRISPR/Cas9 to generate mutant cell lines and assess metabolic changes. Additional duties include but are not limited to: animal surgeries, animal husbandry, DNA preparation, RNA isolation, protein purification and preparation, PCR-based genotyping, RT-PCR, Western Blotting, molecular subcloning, cell culture, immunofluorescence, live cell imaging, cell perfusion as well as NMR spectroscopy and spectral analysis.
The research interests of the Penn Image-Guided Intervention (PIGI) Laboratory lie at the intersection of image-guided interventions, cancer biology and molecular imaging. The lab utilizes a multidisciplinary approach from in vivo animal models of cancer, biochemistry, molecular biology to molecular imaging strategies emphasizing translation with the ultimate goal of leveraging findings to develop novel imaging and therapeutic strategies for patients. The ideal candidate will be self-motivated, enthusiastic, and have excellent organizational skills. This position offers the opportunity to participate in an innovative research environment, to contribute to the foundation of a unique research laboratory and to gain exposure to an innovative and collegial research community within the Departments of Radiology and Cancer Biology as well as supervising and mentoring trainees.
We seek candidates who embrace and reflect diversity in the broadest sense. The University of Pennsylvania is an EOE. Minorities/women/individuals with disabilities/protected veterans are encouraged to apply.
The University of Pennsylvania values diversity and seeks talented students, faculty and staff from diverse backgrounds. The University of Pennsylvania is an equal opportunity and affirmative action employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status or any other legally protected class. Questions or concerns about this should be directed to the Executive Director of the Office of Affirmative Action and Equal Opportunity Programs, University of Pennsylvania, 421 Franklin Building, 3451 Walnut Street, Philadelphia, PA 19104-6205; or (215) 898-6993 (Voice) or (215) 898-7803 (TDD).
Internal Number: 66960
About University of Pennsylvania
Penn has a long and proud tradition of intellectual rigor and pursuit of innovative knowledge, begun by Benjamin Franklin in 1740. That tradition lives today through the creativity, entrepreneurship, and engagement of our faculty, students, and staff. Academic life at Penn is unparalleled, with an undergraduate student body of 10,000 from every U.S. state and around the world. The entering class of 2015 is the most talented and diverse in Penn's history. Consistently ranked among the top 10 universities in the country, Penn welcomes an additional 10,000 students to our top-ranked graduate and professional schools.