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Posted Job Title
Research Specialist C
Job Profile Title
Research Specialist C
Job Description Summary
The primary function of this position is to coordinate and strategically process and catalog separately sample intake from each of multiple clinical studies for the breast 2-PREVENT Translational Center of Excellence studies. This individual will independently work with project leaders who are developing approaches for the isolation and analysis of circulating tumor material (CTC, DTC, ptDNA) from cancer patient samples and rodent models. Core responsibilities will include retrieval and complex processing of bone marrow and whole blood samples, as well as processing, embedding, sectioning and staining of fixed and frozen tissue samples which will late be analyzed under the microscope. Strict organizational and storage criteria must be adhered to. Special emphasis will be placed on techniques in morphology, histology, immunohistochemistry, immunofluorescence and microscopy. Additional responsibilities may include working within the team with other research specialists in extracting and amplifying genetic material from captured CTC/DTCs and independently conducting IHC and IF based experiments designed to screen for DTCs. This cutting edge work will be done in a highly collaborative manner together with laboratories in the Department of Pathology as well as physician scientists in the Department of Cancer Biology in the Perelman School of Medicine. Given the highly collaborative nature of this work and the need for coordination with multiple clinical trial investigators, excellent organization and communication skills are critical. Responsibilities will also include some administrative duties such as ordering of lab supplies, monitoring and calibration of equipment, and organization of data collected on clinical samples.
Develop new approaches for the isolation and analysis of circulating tumor material (CTC, DTC, ptDNA) from ongoing clinical and pre-clinical drug trials focused on breast cancer dormancy and recurrence. Core responsibilities will include processing, cataloging, and assaying bone marrow and whole blood samples. Maintaining project specific sample databases to track assay results and sample inventories. Processing, embedding, sectioning an staining of fixed and frozen tissue samples. Independently conducting IHC and IF based experiments designed to screen for DTSc. Performing microscopic analysis and documentation via digital photography. Strict organizational and storage criteria must be adhered to. This position involves advanced techniques in morphology, histology, immunohistochemistry, immunofluorescence and microscopy. Projects will be executed in a highly collaborative manner together with laboratories in the Penn School of Engineering, the Department of Pathology, and physician scientists in the Department of Cancer Biology in the Perelman School of Medicine. Given the highly collaborative nature of this work and the need for coordination with multiple clinical trial investigators, excellent organization and communication skills are critical. Responsibilities will also include administrative duties such as preparing and presenting project reports.
This position is contingent on funding.
Bachelor's Degree and 3 to 5 years experience or equivalent combination of years and experience required.
Job Location - City, State
Department / School
Perelman School of Medicine
$42,953.00 - $77,315.00
Affirmative Action Statement Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.
Special Requirements Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
Internal Number: JR00000986
About University of Pennsylvania
Penn has a long and proud tradition of intellectual rigor and pursuit of innovative knowledge, begun by Benjamin Franklin in 1740. That tradition lives today through the creativity, entrepreneurship, and engagement of our faculty, students, and staff. Academic life at Penn is unparalleled, with an undergraduate student body of 10,000 from every U.S. state and around the world. The entering class of 2015 is the most talented and diverse in Penn's history. Consistently ranked among the top 10 universities in the country, Penn welcomes an additional 10,000 students to our top-ranked graduate and professional schools.