As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem solving skills and dedication to build stronger minds and a healthier world. UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty. All of which has allowed the UW to be nationally recognized as a "Great College to Work For" for four consecutive years.The Department of Comparative Medicine (DCM) is one of 12 basic science departments in the School of Medicine. The mission of the department is to advance knowledge and improve the health and welfare of humans and animals through excellent service support, biomedical research, and teaching. DCM is the central laboratory animal medicine resource at the University of Washington, supporting over 114,000 assignable square feet of animal facilities with an average daily census in excess of 100,000 animals across multiple species (e.g., rodents, rabbits, swine, and zebrafish). The department employs over 175 individuals who provide a comprehensive range of animal husbandry, veterinary, and laboratory services across numerous vivaria. The UW animal care program is accredited by the Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) and provides services to over 400 principal investigators. Faculty members, postdoctoral fellows and residents (laboratory animal medicine and pathology) conduct basic and clinical research on a wide range of subjects including, but not limited to, comparative aspects of infectious disease, aging, cancer biology and genetics. The Department of Comparative Medicine currently has an outstanding opportunity for a full time Research Scientist/Engineer 2 position within the University of Washington Center for Lung Biology to work with well-established investigators from the Department of Comparative Medicine and Division of Pulmonary, Critical Care and Sleep Medicine. This research position will support studies that use mouse models to measure pulmonary inflammation and physiology in genetically engineered mouse strains with a focus on mouse models of asthma. It will also assist with studies using mice models to define the pulmonary host response to influenza virus. Animal related work will use established protocols to measure alterations in immune cells, mRNA, and proteins with the use of quantitative PCR, ELISA, histopathology, and flow cytometry. Other tasks will include performing flow cytometry and cell culture. Work with cell cultures will be translational requiring the isolation and characterization of mouse and human leukocyte populations. Job Description:Responsibilities:Job responsibilities for this position will include, but are not limited to:Providing technical support for investigators using mouse models of asthma and influenza lung infection;Performing studies using flow cytomery as a tool to phenotype immune cells in biological samples obtained from mice and humans;Assisting with supervision and oversight of genetically engineered mouse colonies;Fixing tissues using standard laboratory protocols and submitting samples to the histology and imaging core;Processing tissues samples and cells for mRNA extraction;Performing in vitro studies with primary cells cultures obtained from mice and humans and performing cell activation and/or inhibitor studies;Writing detailed protocols, maintaining thorough laboratory notebooks, and overseeing laboratory databases;Ordering products and reagents, handling shipments, and attending to other administrative duties as needed; and providing input on decision processes required to run the lab.Minimum Requirements:Bachelor's degree in biology, immunology, or bioengineering and a minimum of three years of job-related experience.Experience working with mouse models of human disease.Experience with flow cytometry.Cell culture experience.Ability to be detail oriented, proactive, organized, and produce high quality work, both independently and collaboratively.Excellent time and project management skills.Ability to work under condensed timelines and realign workload according to shifting priorities.Ability to work on diverse teams of people and with multiple ongoing projects.Conditions of Employment:Must be able to work comfortably in an animal research facility.Punctuality and regular attendance are critical components of this position.Application Process:The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select "Apply to this position". Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your "My Jobs" page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.