This position will assist Principal Investigator to conduct research in cellular and molecular physiology in the Center for Diabetes and Metabolic Diseases within the Wells Center for Pediatric Research. The position entails day-to-day management of laboratory operations and personnel; investigative research aimed at: the study of pancreatic beta cell survival and adaptation to stress, islet gene transcription and chromatin structure, and cytokine signaling in the context of type 1 and type 2 diabetes; small animal (mouse) handling and mouse colony maintenance; protocol development and maintenance, data analyses, and writing results; training and supervising student workers and other research staff; and coordinating regulatory compliance and paperwork for Principal Investigator.
Primary Responsibilities Include:
Assist Principal Investigator by working independently and with collaborators on experimental design, protocol development, and scientific project management, tabulate and compute project results, execute data analysis and write results for reports and publication. This also includes training personnel and student on techniques and analysis, coordination of assignment and monitor task completion, and supervision of graduate and work-study students, graduate students and research technicians. Maintain knowledge of scientific trends through readings, conferences and seminars. Review literature to enhance or improve laboratory procedures and methods.
Manage and conduct research projects and experiments involving small animals, including, but not limited to: Perform cell and molecular biological techniques, such as PCR, western blotting, flow cytometry, and confocal microscopy, and maintaining mouse colonies, including setting up and maintaining breeder cages, maintaining non-breeding cages, animal handling, such as weaning, ear notching, tail snips, dosing, and maintaining colony records.
General laboratory management duties, including order lab supplies, maintain inventory and reagents, assist with the maintenance of regulatory monitoring and paperwork (IACUC, Biosafety, Laboratory Safety, and Radiation Safety), set-up and maintenance of laboratory equipment, and schedule laboratory meetings and presentations.
REQUIRED: Bachelor’s degree in a science major from accredited institution, plus 3 years lab experience; OR Master’s degree in science from accredited institution.
Skills in cellular and molecular biology and advanced skills in animal handling. Hands on laboratory experience and the ability to learn quickly; ability to function independently and conduct experiments; experience in mouse and small animal colony maintenance and/or small animal surgery. Ability to problem solve. Experience with statistical software packages.
Salary Plan: PAE
Salary Grade: 3RS
Campus: IUPUI - Indianapolis
Department: PED-ENDOCRINOLOGY BASIC RES (IN-PENB-IUINA)
Internal Number: 72227
About Indiana University
Founded in 1820, Indiana University is the state’s public university system, comprised of two core campuses—IU-Bloomington and IUPUI—and six regional campuses located throughout the state. Combined, the total student population is more than 114,000 undergraduate, graduate and professional school students. IU is one of the largest employers in the state, with over 20,000 faculty and staff. Indiana University is an equal employment and affirmative action employer and a provider of ADA services. Diversity and inclusion remains a core commitment to IU’s mission to cultivate an educational environment that supports equal access, participation and representation on all of its campuses and that provides educational and career opportunities for all.